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Journal of Diagnostic Medical Sonography
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The Role of Ultrasound in Chorionic Villus Sampling

A Review

Michael F. Jeffery, B.Sc., RDMS

#201-2315 West 5th Avenue, Vancouver, British Columbia, V6K 1S6.

The use of ultrasound as a guidance tool for chorionic villi sampling for prenatal diagnosis in the first trimester is discussed. Three sampling techniques used in the first trimester are reviewed: endoscopy, blind aspiration, and the combination of endoscopy and aspiration with ultrasound guidance. A review of the literature found that ultrasound guidance provided the highest success rate in obtaining chorionic villi for chromosomal analysis and enzyme determination. Concerns regarding proper scanning technique for localizing the implantation site for sampling are discussed.

Key Words: chorion biopsy. chorionic villi sampling • early prenatal diagnosis

Journal of Diagnostic Medical Sonography, Vol. 2, No. 3, 135-140 (1986)
DOI: 10.1177/875647938600200303
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