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Arthrogryposis Multiplex Congenita

Florida Hospital College of Health Sciences, Orlando, FL, charlotte.henningsen{at}fhchs.edu

Sarah L. Smith, AS, RDMS

Florida Hospital College of Health Sciences, Orlando, FL

Arthrogryposis multiplex congenita (AMC) is a disorder that encompasses a range of severity of congenital joint contractures from mild to severe. The etiologies of this condition are numerous but can generally be classified into endogenous and exogenous factors. Endogenous factors are related to those conditions that originate within the fetus and can further be classified into central nervous system disorders, musculoskeletal abnormalities, and abnormalities of the joints and connective tissues. The sonographic presentation of AMC includes decreased or absent fetal movement with contractures of multiple extremities. Treatment and medical management of AMC depends on the severity of the contractures and the absence or presence of associated syndromes. Accurate diagnosis of AMC allows for accurate prenatal counseling regarding future morbidity and mortality of the fetus and includes options regarding treatment, medical management, and pregnancy termination depending on the severity of the condition.

Key Words: arthrogryposis • akinesia • contractures • endogenous • exogenous

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