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Second-Trimester Findings Associated With Nonimmune Hydrops

Family Health Center, Waco, Texas, fifteenfortymps{at}yahoo.com

Nonimmune hydrops fetalis (NIHF) is a fetal condition in which an overaccumulation of fluid in the interstitial tissues of the fetus occurs. NIHF is a separate condition from fetal immune hydrops caused by Rh incompatibility. There are multiple etiologies associated with NIHF, such as genetic disorders, fetal anemia, infectious diseases, twin-to-twin transfusion syndrome, and cardiovascular abnormalities. NIHF is an uncommon, predominantly fatal finding. The obstetric patient may present large-for-gestational age but is Rh compatible. Fetal anatomy may demonstrate multiple findings, including gross skin thickening, polyhydramnios, pleural or pericardial effusions, fetal ascites, and thickened placenta.

Key Words: nonimmune hydrops • skin edema • sonography • pleural effusion • fetal ascites

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