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Journal of Diagnostic Medical Sonography
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Antenatal Sonographic Findings in Trisomy 21

Pamela K. Clark, RT, RDMS

Toni L. Hurton, BS, RDMS

Janice Stryker, MS

Beryl R. Benacerraf, MD

Departments of Obstetrics and Gynecology and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

A case involving a 20-week fetus with Down syndrome is described. Sonographic signs of trisomy 21 included a thickened nuchal fold, heart defect, short femur and humerus length, pyelectasis, hypoplasia of the middle phalanx of the fifth digit, and an abnormal facial profile.

Key Words: Down syndrome • trisomy 21 • chromosomal anomaly • nuchal fold

Journal of Diagnostic Medical Sonography, Vol. 8, No. 6, 316-319 (1992)
DOI: 10.1177/875647939200800604
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