Journal of Diagnostic Medical Sonography

 

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First published on February 26, 2008, doi:10.1177/8756479308315225

Journal of Diagnostic Medical Sonography 2008;24:93.

A more recent version of this article appeared on March 1, 2008

Article

Second-Trimester Findings Associated With Nonimmune Hydrops

Margaret Smith-Weaver*

* To whom correspondence should be addressed. E-mail: fifteenfortymps{at}yahoo.com.


  Abstract
Nonimmune hydrops fetalis (NIHF) is a fetal condition in which an overaccumulation of fluid in the interstitial tissues of the fetus occurs. NIHF is a separate condition from fetal immune hydrops caused by Rh incompatibility. There are multiple etiologies associated with NIHF, such as genetic disorders, fetal anemia, infectious diseases, twin-to-twin transfusion syndrome, and cardiovascular abnormalities. NIHF is an uncommon, predominantly fatal finding. The obstetric patient may present large-for-gestational age but is Rh compatible. Fetal anatomy may demonstrate multiple findings, including gross skin thickening, polyhydramnios, pleural or pericardial effusions, fetal ascites, and thickened placenta.


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